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Note that these dose ranges are an approximation, count on distinct conduct/activity, and in certain species dependant on only 1 or 2 studies and drug administrations. The species differences may very well be due to the pharmacokinetics and metabolism variations, along with the physiology of the specific animal versions. Additionally it is likely that immediate mg/kg comparison is not really ideal throughout species and interspecies scaling component is necessary for the significant comparison.
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“I believe it should be dialed again a little bit, just so we can definitely ensure that we’re doing this with the right intentions and taking the time to really recognize what’s taking place.”
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DiPT generates small-expression Visible and auditory hallucinations which include hearing voices and weird desire states at substantial doses and auditory distortion with deep tones at low doses [82].
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